Fanucci Group

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Week #

Dates

Topic

Pres.

Y/N

Presentor #1

Presentor #2

1

01/06;01/08

Cell Membranes/ Chemical Structure of Lipids

reading:Prasad1;Yeagle1, Yeagle2, YeagleStruc1a

lectureppt:1,

 

N

Note: the weeks there are no presentations we will only have 1 period of lecture on Tuesday.

 

2

01/13;01/15

Hydrophobic Effect/Amphipathic Molecule Self Assembly/Membrane Models

Prasad4, YeaglStruc1b, Gennis2a, Yeagle3

lectureA,lectureB

 

N

 

 

3

01/20;01/22

Methods for Characterizing Lipid Assembly Size and Morphologies: EM, X-ray,Phase Transitions : DSC

Yeagle 4a, Gennis2b

lecture(thurs)

N

 

 

4

01/27; (01/29)

Lipid Bilayer Structure /Detergents and Membrane Solubilization

YegStruc2a, YegStruc2b, Gennis2a, YeagStruc5a

BBA2004:ReviewDetergents

lecturenotes

Y

Ian (second messengers)

Kyle (second messengers)

5

02/03; 02/05

Molecular organization and molecular motions – Methods of Study- X-ray, DSC, IR

Gennis5a, Gennis5b, Yeagle4b, Yeagle4c,

lecturenotes

Y

Matt (cubic phase lipids)

Rochelle (Unusual Phospholipids)

6

02/10; 02/12

Methods of Study (cont) EPR/NMR/

yeagleStruc5b,c,

Y

Jacina (Nonlamellar lipids)

William (CPPs)

7

02/17; 02/19

Cholesterol/lipid rafts Fluorescence FRET/FRAP etc

YeagleChapt5

ergosterol-PCphasediagram; cholesterolrafts;

lecturenotes; lecture notes-rafts

Here are papers that correspond to lecture note info on rafts: 1, 2, 3 , 4

 

Y

Tao (Rafts)

Anna (anesthetics)

8

02/23; 02/26

Hydrophobicity Scales – molecular partitioning Antibiotic peptides/cell penetrating peptides/ Anesthetics-small molecule partitioning

reviewCPPS, review AMPs

lecturenotes

Y

Lamees (Hydrophobicity scales)

Whitney (rafts)

9

(03/03; 03/05)

Guest Lecture (03/03)

Mid Term – in class (03/05)

 

N

Note:I am out of town. There will be a proxy for the exam.

Attendance will be taken at the Guest Lectures and questions will appear on the final!

10

Spring break

NO CLASSES

N

 

 

11

(03/17; 0319)

Guest Lecture (03/17)

N

 

Attendance will be taken at the Guest Lectures and questions will appear on the final!

12

03/24; 03/26

Lipid Assymmetry/Lipid flip-flop /chemical modification /hydrophobic mismatch

Gennis4

leecture notes, lecture notes

Y

Lu (CPPs)

Yong (AMPs)

13

03/31; (04/02)

PAM MORRIS - WIKI on Tuesday

NO CLASS ON THURSDAY

Y

Bogdan (Cpps)

Jie (AMPs)

14

(04/07); 04/09

Membrane fusion/membrane curvature

NO CLASS ON TUESDAY

membrane curvature lecture

membrane fusion lecture

Y

Li (Fusions)

You (hydrophobic mismatch)

Hao (receptors)

Yuri (Membrane curvature)

15

04/14; 04/16

Membrane proteins receptors/signal transduction

more membrane fusion

Y

Star (Receptors)

Zheng (Receptors)

16

04/21

No Final, but we will have class. I expect you to have your first draft of your wiki page completed PAM will come back for help uploading figures and tables.

N

 

 

17

Finals’ Week

WIKI page due ..